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Publication of scientific article in Scopes index
2022-06-26
Dr. Younus K. Jabur, a researcher at the Renewable Energy Research Center – University of Anbar in cooperation with researchers. Publish a scientific article in international journal "Russian Journal of Organic Chemistry" that has Scopus index titled:
"Synthesis of Some New Pyrrolo[3,4-f]isoindole Derivatives Bearing a 1,3-Thiazolidin-4-one Moiety"
In the present study, A series of new N,N′-bis[4-oxo-2-(pyridine-2-yl)-1,3-thiazolidin-3-yl]-2,2′-[1,3,5,7-tetraoxo-5,7- dihydropyrrolo[3,4-f]isoindole-2,6(1H,3H)-diyl]diacetamide derivatives were synthesized with acceptable yields starting from pyromellitic dianhydride which was treated with potassium cyanate in DMF under reflux to afford pyromellitic diimide. The latter was further reacted with ethyl chloroacetate in refluxing absolute ethanol to yield diethyl 2,2′-[1,3,5,7-tetraoxo-5,7-dihydropyrrolo[3,4-f]isoindole-2,6(1H,3H)-diyl]diacetate. The subsequent treatment with excess hydrazine hydrate (80%) gave 2,2′-[1,3,5,7-tetraoxo-5,7-dihydropyrrolo[3,4-f]isoindole-2,6(1H,3H)-diyl] diacetohydrazide which was condensed with substituted pyridine-2-carbaldehydes in ethanol in the presence of a catalytic amount of glacial acetic acid. The resulting Schiff bases underwent cyclization with thioglycolic acid in the presence of ZnCl2 to produce the corresponding 1,3-thiazolidine derivatives. The product structures were confirmed by FTIR and 1H NMR spectra and elemental analyses.
Publication detail
https://link.springer.com/article/10.1134/S1070428022030149
